Betatrophin

Human Betatrophin is encoded by C19orf80 [chromosome 19 open reading frame 80]. In databanks, TD26 is used as a synonym for Betatrophin and refers to mouse gene Gm6484.

Betatrophin is a hormone identified by Yi et al (2013) in a mouse model of insulin resistance that induces dramatic pancreatic Beta-cell proliferation and Beta-cell mass expansion. (NOTE: Yi et al (2017) have retracted their original publication, reporting that experiments performed by others and repetition of their original experiments do not support the conclusion that betatrophin causes specific ... ... ... ...
 
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Entry last modified: March 2018