Beta-Hemolysin |
Beta-IG-M1 |
EC3.4.24.19 |
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[TGF-beta-inducible gene H3] Abbr. also BIGH3. This gene (approved gene symbol TGFBI (transforming growth factor-beta-induced 68 kDa protein; TGF-beta-induced 68 kDa protein) has been identified originally as one the expression of which is upregulated in human adenocarcinoma cells treated with TGF-beta.
The human gene has been mapped to human chromosome 5q31, a region frequently deleted in preleukemic myelodysplasia and leukemia (see also: 5q minus syndrome). The cDNA encodes a protein of 683 amino acids. It contains an amino-terminal signal sequence and a carboxy-terminal
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