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BRBP1

This targeting peptide, MYPWTEPSYLSN, has been identified by phage display library screening for peptides targeting 231-BR cells, a subclone of MDA-MB-231 human breast carcinoma cells that exclusively metastasizes to the brain. The peptide also preferentially homes to xenotransplanted tumors derived from these cells, accumulates at the tumor site, and is internalized efficiently by cells (Fu et al, 2014),

Fu et al (2015) have created a compound peptide containing BRBP1, TAT cell penetrating peptide, and the pro-apoptotic KLAKLAK sequence. This ... ... ... ... ... Subscribe to continue reading! ... ...

 

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