BGR

[Beta-glucan receptor] This receptor is a type 2 transmembrane receptor with a single extracellular carbohydrate recognition domain and an ITAM motif in its cytoplasmic tail (Willment et al, 2001). Human BGR is expressed widely and functions as a pattern recognition receptor that recognizes a variety of beta-1,3-d-Glucans and beta-1,6-d-Glucans, glucose polymers found in the cell walls of plants, fungi, and bacteria that are considered to function as pathogen-associated molecular patterns.

The human receptor mRNA is alternatively spliced, resulting in two major (BGRA (Beta-glucan receptor A = dectin-1A) and BGRB ( ... ... ... ...
 
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