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Alanyl-tRNA synthetase

approved gene symbol: AARS; called also Alanine-tRNA ligase; abbr. also AlaRS. In the nomenclature of enzymes the synthetase has been given the designation EC6.1.1.7. The enzyme, which belongs to the class of aminoacyl-tRNA synthetases, has been identified independently as NY-REN-42 [Renal carcinoma antigen NY-REN-42] (Scanlan et al, 1999). Alanyl-tRNA synthetase catalyzes the attachment of alanine to tRNA-ala and thus plays an essential role in protein synthesis. Shiba et al (1995) have reported the primary structure of human Alanyl-tRNA synthetase, showing also that both the Escherichia coli and the human ... ... ... ... ... Subscribe to continue reading! ... ...

 

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