AFSSWGamide |
AFTCHCRRSCYSTEYSYGTCTVMGINHRFCCL |
Chi3l4 |
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This murine stromal cell line has been derived from day 14 gestational fetal liver adherent cells immortalized by the introduction of a retrovirus containing a temperature-sensitive SV40 T-antigen (Moore et al, 1997). AFT024 cells express betaglycan and membrane bound heparan sulfate, secrete Chondroitin sulfate into the conditioned medium. The cells do not appear to express syndecan-1 and syndecan-2 (Arcanjo et al, 2002).
The cells maintain long-term repopulating murine stem cells in vitro (see also: hematopoiesis, MRA,
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