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ADAM28

[a disintegrin and metalloprotease domain 28; ADAM metallopeptidase domain 28] This protein is a member of the ADAM protein family. It is known also as MDC-L [metalloproteinase-like disintegrin-like cysteine-rich protein L], a protease expressed predominantly on human lymphocytes (Roberts et al, 1999).

The protein is expressed by human lymphocytes in a secreted form (MDC-Ls, ADAM28s) and a transmembrane form (MDC-Lm, ADAM28m) (Roberts et al, 1999). Murine ADAM28 is expressed in thymic epithelial cells and developmentally related tissues including the trachea, thyroid, stomach, and lung, but not in lymphocytes ... ... ... ... ... Subscribe to continue reading! ... ...

 

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