ACT-2
[Immune activation gene-2] ACT-2 is known also as G26, pAT744, LAG-1, and MIP-1-beta (macrophage inflammatory protein see: MIP). The new designation is CCL4.
The human ACT-2 gene, designated SCYA4 (see also: SCY family of cytokines), maps to chromosome 17q21-q23 (Napolitano et al, 1991). Studies of sequence homology and genome organization have shown that ACT-2 belongs to the family of chemotactic cytokines known as Chemokines.
ACT-2 is a factor secreted by T-cells, B-cells, monocytes and various tumor
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