ABIN-3

[A20-binding inhibitor of NF-kappa-B activation-3] This protein has been identified as LIND [Listeria induced] as its expression is induced in macrophages by infection with Listeria monocytogenes (Staege et al, 2001). Wullaert et al (2007) have renamed the protein ABIN-3 as it shows sequence relationship and functional similarity with ABIN-1 and ABIN-2. The approved gene symbol is TNIP3 [TNFAIP3 interacting protein 3].

ABIN-3 binds to A20 and inhibits NF-kappa-B activation induced by TNF-alpha, IL1, and 12-O-tetradecanoyl-phorbol-13-acetate. Strong expression of ABIN-3 is seen in ... ... ... ...
 
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Entry last modified: July 2012