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ABCD-1

The murine ABCD-1 is a protein of 68 amino acids that belongs to the group of chemotactically active cytokines known as CC-Chemokines. The gene (gene symbol SCYA22; new designation CCL22) was isolated using the suppression subtractive hybridization method by stimulation of pro/pre B-cells (see also: hematopoiesis) with antibodies against CD40 and IL4 to mature S-mu-S-epsilon-switched cells (Schaniel et al, 1998, 1999). The protein is identical with MDC and has been described also as DC/B-Ck and STCP-1.

mRNA levels in lung, unstimulated splenic cells, thymocytes ... ... ... ...
 
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Entry last modified: March 2002



 
 
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