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22 kDa factor

This factor is produced by mitogen-stimulated mononuclear cells from human peripheral blood. It induces the production of human IFN-beta in cultured human fibroblasts, thereby rendering these cells resistant to virus infection (Bunning et al, 1986; Content et al, 1985). Van Damme et al (1985) have shown that the factor is related to IL1. The factor is identical with IL1-beta (see: IL1).

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