wispostatin-3

This bioactive peptide fragment is derived from WISP-3 [Wnt-1 induced secreted protein-3; Wnt1-inducible signaling pathway protein-3], a member of the CCN family of secreted cysteine-rich growth regulators (Karagiannis and Popel, 2007). Wispostatin-3 (TKWTPCSRTCGMGISNRV; Thr-Lys-Trp-Thr-Pro-Cys-Ser-Arg-Thr-Cys-Gly-Met-Gly-Ile-Ser-Asn-Arg-Val) corresponds to residues 232-249 of the WISP-3 gene (WISP-3(232-249)) (Karagiannis and Popel, 2008). The primary structure of this peptide is similar to the thrombospondin type 1 domains found in thrombospondin-1, thrombospondin-2, the metalloproteinases ... ... ... ...
 
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Entry last modified: July 2012