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wispostatin-3

This bioactive peptide fragment is derived from WISP-3 [Wnt-1 induced secreted protein-3; Wnt1-inducible signaling pathway protein-3], a member of the CCN family of secreted cysteine-rich growth regulators (Karagiannis and Popel, 2007). Wispostatin-3 [TKWTPCSRTCGMGISNRV] corresponds to residues 232-249 of the WISP-3 gene (WISP-3(232-249)) (Karagiannis and Popel, 2008). The primary structure of this peptide is similar to the thrombospondin type 1 domains found in thrombospondin-1, thrombospondin-2, the metalloproteinases ADAMTS1 and ADAMTS8. The peptide ... ... ... ... ... Subscribe to continue reading! ... ...

 

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