wispostatin-2

This bioactive peptide fragment (see also: cryptides) is derived from WISP-2 [Wnt-1 induced secreted protein-2; Wnt1-inducible signaling pathway protein-2], a member of the CCN family of secreted cysteine-rich growth regulators (Karagiannis and Popel, 2007). Wispostatin-2 (TAWGPCSTTCGLGMATRV; Thr-Ala-Trp-Gly-Pro-Cys-Ser-Thr-Thr-Cys-Gly-Leu-Gly-Met-Ala-Thr-Arg-Val) corresponds to WISP-2(199-216) (residues 199-216 of the WISP-2 gene) (Karagiannis and Popel, 2008). The primary structure of this peptide is similar to the thrombospondin type 1 domains found in thrombospondin-1, thrombospondin-2, the ... ... ... ...
 
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Entry last modified: July 2012