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tumor-associated neutrophils

[tumor-associated neutrophil]

abbr. TANs. This cell type constitutes a population of neutrophils recruited by many cancers into the tumor mass. These cells can enhance the growth of tumor cells and have been implicated in aggressive tumor behavior (Houghton et al, 2010; Mantovani et al, 2009).

Tumor-associated neutrophils in lung cancer have been shown to be able to polarize to two different phenotypes, referred to as N1 and N2. N1 neutrophils [N1 tumor-associated neutrophils] (abbr. N1 TANs) have been shown to inhibit cancer development. N2 neutrophils [N2 tumor-associated neutrophils] (abbr. N1 TANs ... ... ... ... ... Subscribe to continue reading! ... ...

 

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