pBMP9

This is a peptide derived from the bone morphogenetic peptide BMP9. The peptide (CGGKVGKACCVPTKLSPISVLYK; Cys-Gly-Gly-Lys-Val-Gly-Lys-Ala-Cys-Cys-Val-Pro-Thr-Lys-Leu-Ser-Pro-Ile-Ser-Val-Leu-Tyr-Lys) retains the bioactivity of the parent protein in promoting osteogenic differentiation (Bergeron et al, 2007, 2009). Lord et al (2010) have reported that pBMP9 dose dependently reduces the proliferation of human white pre-adipocytes without affecting the number of apoptotic cells. The peptide activates the SMAD1 SMAD5 SMAD8 pathway, enhances the levels of adipocyte ... ... ... ...
 
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Entry last modified: March 2014