osteomimicry

this term has been used to refer to the ability of certain types of bone-metastatic cancer cells to acquire a phenotype resembling that of osteoblasts. Such cells have been reported variously as cancer-associated osteoblast-like cells or tumor-associated osteoblast-like cells (see also: osteoblast-like cells). In prostate cancer, these cancer cells express bone matrix proteins and modulate bone cell crosstalk, resulting in the alteration of physiological bone remodeling processes that leads to enhanced tumor survival and proliferation (for overview see also: Furesi G et al, 2021). Furesi G et al (2021) have suggested that the contact between tumor cells and osteoblasts turns normal osteoblast ... ... ... ...
 
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Entry last modified: March 2024