organoptosis

this descriptive term, coined by Skulachev VP et al (2002) in analogy with a cell death mode known as apoptosis, has been suggested to refer to the loss of an entire organ during ontogeny. The process may involve any kind of programmed cell death. An example of organoptosis would be the disappearance of the tail during the development of a tadpole into a frog or the disappearance of the vestigial tail in humans. A lassical example involving cell death by apoptosis is the removal of interdigital mesenchymal cells during the formation of digits. For other examples see also: Voss AK and Andreas Strasser A (2020) and the references cited therein.

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