immunoediting

This term, unlike the term cancer immunosurveillance, which pertains to the elimination of cancer cells by the immune system, refers to the observation that the immune system can have host-protective as well as tumor-promoting actions on developing cancers (Pagés and Kroemer, 2011; Schreiber et al, 2011; Mittal et al, 2014; Teng et al, 2015).

Initially, cancer cells constitute a heterogeneous population of cells, sometimes referred to as unedited tumor cells (unedited cancer cells). Highly immunogenic tumor cells in this population may be eliminated, whereas poorly immunogenic tumor cells, sometimes called edited tumor cells (edited cancer cells ... ... ... ... ... Subscribe to continue reading! ... ...