Gastrulation-defective |
GATA-1 |
lysosomal integral membrane protein-1 |
||
also: 3D gastruloids. These terms pertain to embryo-like structures formed by pluripotent embryonic stem cells under three-dimensional cell culture conditions. These self-organizing cell aggregates (recapitulate the axial organization of post-implantation embryos (see also: sphere forming assay for other types of cell aggregates).
Gastruloids display key features of mammalian development after implantation (Turner et al, 2017; van den Brink et al, 2013, 2020). The self-organization process reveals different degrees of pluripotency of the participating cells (Cermola F et al, 2021). Hashmi et al (2022) have reported that the induction of
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