FLSTLTIDGV |
flt-1 |
alpha-hemoglobin(133-141) |
||
[fms-like tyrosine kinase; also known as flt-1] Another designation is FRT [fms-related tyrosine kinase]. The receptor is being referred to also as VEGFR1. Soluble forms of the receptor are being referred to as sFlt-1 or sVEGFR1. Soluble forms of the receptor are released under physiological conditions and may be overproduced in some pathologies (Wu et al, 2010).
flt protein is related to fms (the receptor for M-CSF). flt is a transmembrane receptor protein that encodes a cytoplasmic domain functioning as a tyrosine-specific protein kinase. It is related to another receptor called KDR and a
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