cerebellins

Cerebellins constitute a family of secreted proteins that form homomeric or heteromeric complexes (Iijima et al, 2007) and may generally serve as a new class of transneuronal cytokines involved in the regulation of synapse development and synaptic plasticity in various brain regions (Yuzaki, 2008, 2010). The precursor proteins contain a C1q-like domain found in complement component C1q subunits (see also: C1q family).

Cerebellin encoded by the cerebellin-1 gene (CBLN1) (also called precerebellin, cerebellin precursor protein 1) is a hexadecamer peptide (SGSAKVAFSAIRSTNH; ... ... ... ...
 
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Entry last modified: July 2017