WISH

This term has multiple meanings:

(-1-) A transformed human cell line with epitheloid morphology originally established from amnion epithelium (Hayflick, 1961). This cell line is used to assay human IFN-alpha and IFN-gamma. The interferons (see: IFN) are quantified by performing a cytopathic effect inhibition assay of vesicular stomatitis virus (VSV). The cells are significantly more sensitive for both IFN-alpha and IFN-gamma when EMCV (encephalomyocarditis virus) is used instead of VSV.

The antiviral state of these cells is enhanced in the presence of mixtures of human ... ... ... ...
 
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Entry last modified: March 2002