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VSGP

[Vascular smooth muscle cell growth-promoting factor] This factor has been isolated from bovine ovarian follicular fluid as a stimulator of vascular smooth muscle cell proliferation (Miyamoto et al, 2001). Bovine and human VSGP are orthologs of rat F-spondin, a protein identified as a guidance cue for neurons. The protein is also being referred to as SPON1 [spondin-1].

VSGP does not affect the proliferation of human umbilical vein endothelial cells, but it inhibits cell migration of these cells in response to VEGF or bFGF ... ... ... ... ... Subscribe to continue reading! ... ...

 

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