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Uperin 3.6

Uperin 3.6 is a peptide of 17 amino acids (GVIDA5AKKVV10NVLKN15LFamide) (Chia et al, 1999). It is a wide-spectrum antibiotic peptide isolated from the Australian toadlet, Uperoleia mjobergii (Giacometti et al, 2005). Giacometti et al (2006) have reported that Uperin 3.6 can be used to prevent endotoxemia and bacterial translocation in bile-duct-ligated rats.

For other proteins/peptides with functions in innate immunity and/or antimicrobial activities see also: Innate immunity and defense peptides Dictionary.

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