UF |
UG |
Renal carcinoma antigen NY-REN-4 |
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The UFO protein (in allusion to the as yet unidentified function of its protein when it was identified by Janssen et al, 1991) is being referred to also as ark [adhesion related kinase], tyro7 [tyrosine-protein kinase 7], JTK11) is a member of a family of receptor tyrosine kinases (see: TAM receptors) and is encoded by a transforming gene that was initially isolated from primary human myeloid leukemia cells by DNA-mediated transformation of NIH 3T3 cells (Janssen et al, 1991). The ligand has been identified as gas-6.
Challier C et al (1996) have reported that UFO is expressed solely in myeloid and erythro-megakaryocytic
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