TWEAK receptor |
twhh |
T-cell replacing factor-1 |
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This protein, referred to also as TNFSF12-TNFSF13 or TNFSF12-13, is encoded by an endogenous hybrid transcript between TWEAK (TNFSF12) and APRIL (CD256, TNFSF13). TWE-PRIL is a transmembrane protein that consists of a TWEAK intracellular, transmembrane and stalk region combined with APRIL as its receptor-binding domain. TWE-PRIL is expressed in human primary T-cells and monocytes.
TWE-PRIL, like APRIL, can stimulate T-cell and B-cell
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