TRIM21

(approved gene symbol) [tripartite motif-containing protein 21] This protein, a member of a large family of proteins containing a tripartite motif, has been identified originally as a target for autoantibody production in systemic lupus erythematosus and Sjögren's syndrome and was termed variously SS-A/Ro autoantigen (SS-A/Ro antigen), Ro/SS-A autoantigen, Ro52 (often: Ro52/TRIM21), SSA1 [Sjögren's syndrome antigen A1], 52 kDa Ro protein. The autoantigen is a ribonucleoprotein particle composed of a single polypeptide and 1 of 4 small RNA ... ... ... ...
 
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Entry last modified: August 2015