TMTP1

[tumor metastasis targeting peptide-1] This peptide, NVVRQ, has been identified as a tumor homing peptide in a screen using a bacterial peptide display system, an alternative to phage peptide display (Yang et al, 2008). TMTP1 specifically binds to a series of highly metastatic tumor cells, including PC-3M-1E8 prostate cancer cells, MDA-MB-435S breast cancer cells, PG-BE1 lung cancer cells, and MKN-45sci gastric cancer cells, in vitro and in vivo. The peptide does not bind to poorly metastatic or non-metastatic cell lines, including PC-3M-2B4 prostate cancer cells, MCF-7 breast cancer ... ... ... ...
 
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Entry last modified: May 2015