TF-alpha |
TF antigen |
PLP-I |
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(approved gene symbol) [Transcription factor A, mitochondrial] TFAM is known also as mtTFA [mitochondrial transcription factor A], MtTF1 [Mitochondrial transcription factor 1], TCF-6 [Transcription factor 6]. TFAM is structurally related to HMGB1 [high mobility group box-1]. It functions as a transcription factor for mitochondrial DNA required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. It binds to DNA in a sequence-independent manner, plays a crucial role in maintaining mitochondrial DNA
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