Tc cells |
TcdA |
Dekafin-22 |
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[T-cell cytokine receptor] This receptor is a member of the type 1 cytokine receptor family, designated T-cell cytokine receptor (TCCR). When challenged in vivo with protein antigen, Th1 T-helper cells of transgenic mice in which the receptor gene has been deleted by targeted disruption do not produce IFN-gamma, which is one of the characteristic features of Th1 T-helper cells. TCCR deficient mice also are more susceptible to infection with an intracellular pathogen, Listeria monocytogenes. Levels of antigen-specific IgG2a, which are dependent on Th1 T-helper cells
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