small non-protein-coding RNAs |
small nucleolar RNA host genes |
NPFHSWGamide |
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[Small nuclear RNA]
abbr. snRNAs. This term usually refers to a group of five non-coding RNAs, about ~150 nucleotides in length, that are localised in the nucleus. Because these RNAs are rich in uridine, they are being referred to also as U snRNAs [uridine-rich small nuclear RNAs]. The snRNAs of the major spliceosome are encoded by multiple genes and pseudogenes in metazoans (Marz et al, 2008) and are usually dispersed in the human genome, whereas human U1 snRNA and U2 snRNA genes exist in large chromosomal clusters (Manser and Gesteland, 1982; Van Arsdell and Weiner, 1984; Westin et al, 1984). Human U1 snRNA
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