scolexins |
Scolopendin 1 |
intermediate tufted cells |
||
This antimicrobial peptide with the sequence SPSEKAGLQPVGRIGRMLKK has been isolated from the centipede Scolopendra subspinipes mutilans. The peptide perturbs antifungal membranes and disrupts calcium ion homeostasis in both the cytosol and mitochondria. The peptide disrupts mitochondrial membrane potential and cytochrome C levels. Fungal cells treated with scolopendin exhibited various features of cell death by apoptosis such as reactive oxygen species accumulation, phosphatidylserine exposure, chromatin condensation, and nuclear fragmentation. Scolopendin-induced cell death also triggers metacaspase activation (Lee et al, 2017).
...
...
...
...
... Subscribe to continue reading!
... ...
Content view restricted ! |
| SUPPORT COPE | Intro | Subdictionaries | New Entries | Contribute data | COPE Credentials |
| # | A | B | C | D | E | F | G | H | I | J | K | L | M | N | O | P | Q | R | S | T | U | V | W | X | Y | Z |
|
Created, developed, and maintained by Dr H Ibelgaufts
|
U L T R A P O S S E N E M O O B L I G A T U R