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SOS1

(SOS = son of sevenless) SOS1 [son of sevenless 1] is the human homolog of the Drosophila melanogaster SOS gene (CG7793) which encodes a positive regulator of ras oncogene function by promoting guanine nucleotide exchange. The activation of the sevenless (sev) receptor tyrosine kinase is required for the specification of cell fate during the development of photoreceptor cells (Webb et al, 1993).

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