sk30/sk89 |
sk89 |
cancer metastasis-initiating cells |
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SK84 (N-terminal serine, C-terminal lysine, 84 residues) is a glycine-rich antimicrobial peptide purified from the larvae of Drosophila virilis. The mature protein is processed from the pseudoprotein GJ19999 from Drosophila virilis, and is very similar to several pseudoproteins from different Drosophila species (Lu et al, 2010). SK84 shows antibacterial activity against Gram-positive bacteria (Bacillus subtilis, Bacillus thuringiensis, Staphylococcus aureus), but has no effect on Gram-negative bacteria (Pseudomonas aeruginosa, Escherichia coli) and fungi (Saccharomyces cerevisiae, Candida albicans).
SK84 is an anticancer peptide that inhibits the proliferation of several cancer
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