SFL

[scatter factor-like] This factor has been found in the conditioned medium of a metastatic clone of the rat bladder carcinoma epithelial NBT-II cell line but not by the tumorigenic parental cell line from which it originated (E-NBT-II). The factor is able to dissociate epithelial clusters of NBT-II or MDCK cells and may be involved in tumor progression (see also: Motogenic cytokines).

The activities of SFL resemble those of hepatocyte growth factor (see: HGF; see: SF (scatter factor)) on these two cell lines. SFL appears to be a factor that is distinct from HGF/Scatter factor since blocking antibodies against rat HGF ... ... ... ...
 
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Entry last modified: March 2012