SAGSCKCKESKSTS |
SAK |
Herpesvirus saimiri HVS13 |
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This peptide, described originally as Peptide SP (Hardy et al, 2000) has been identified by phage display library screening human vascular endothelial cells under hypoxic conditions.
The peptide significantly promotes the proliferation of endothelial cells, induces significant endothelial cell migration, induces significant sprouting in a human aortic ring angiogenesis assay, and induces tube formation on Matrigel but only under hypoxic conditions.
See also: Angiogenesis Dictionary section of this encyclopedia for other entries directly bearing on factors and processes involved in the generation of new blood vessels.
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