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RSV induced factor

The expression of this factor is induced by respiratory syncytial virus (RSV). It can inhibit the proliferative response of human peripheral blood mononuclear cells (PBMC) in vitro. The factor is identical with interferon IFN-alpha (Preston et al, 1995).

RSV induced IFN-alpha inhibits the anti-RSV proliferative response only when added within the first few days of stimulation. Immunosuppression by IFN-alpha may significantly affect the outcome of infection and reinfection with RSV.

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