RNASE3 |
RNASE5 |
Prolactin-like protein J |
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(approved gene symbol) [ribonuclease 4]. Abbr. also RNS4 (Note: Ribonuclease L (RNASEL) has also been referred to as RNS4).
The RNASE4 gene has been cloned by Rosenberg and Dyer (1995). RNASE4 is a member of the superfamily of secreted ribonucleases that shares the same promoters with angiogenin and is co-expressed with angiogenin. RNASE4 protein is able to induce angiogenesis in in vitro, ex vivo, and in vivo assays. RNASE4 also induces neural differentiation of P19 mouse embryonal carcinoma cells and mouse embryonic stem cells. RNASE4 not only stimulates the formation of neurofilaments from mouse
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