REG3-gamma |
Regakine-1 |
COPE version 19.4 |
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[regenerating islet-derived-4] A databank synonym for this protein is GISP [Gastrointestinal secretory protein].
The gene encoding this protein, which is a 17 kDa secreted C-type lectin, has been cloned by Hartupee et al (2001). The gene has been cloned independently as RELP [REG-like protein] by Kaemaeraeinen et al (2003), who have reported upregulated expression in inflammatory and metaplastic gastrointestinal mucosa. REG4 is expressed widely in the gastrointestinal tract. Heiskala K and Andersson (2013) have reported expression of REG4 in selected enteroendocrine cells in the human
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