PLAB |
PLAC8 |
C20orf182 |
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[placenta-specific protein 1; placenta-specific 1] PLAC1, which is a secreted protein, has been identified by Cocchia et al (2000) who reported expression in ectoplacental cone, giant cells, and labyrinthine trophoblasts during mouse embryogenesis and suggested a role in the establishment of the fetomaternal interface. The putative human and murine PLAC1 proteins are 60 % identical and 77 % homologous. Fant et al (2002) have reported that PLAC1 is expressed throughout pregnancy in the human placenta. Expression is regulated by KGF [keratinocyte growth factor] (Fant et al, 2002; Massabbalet al, 2005).
Ablation of PLAC1 expression in
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