NIN1 |
ninein like mouse |
DSPP(629-640) |
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abbr. Nin. This protein has been identified as a centrosomal microtubule-anchoring protein that is essential for the reformation of the interphase centrosome architecture following mitosis (Ou et al, 2002). Delgehyr et al (2005) have proposed that ninein constitutes a molecular link between microtubule-nucleation and -anchoring activities at the centrosome. Stillwell et al (2004) have reported that ninein plays a regulatory role in microtubule nucleation.
Several studies have shown that ninein is a centrosomal autoantigen (Stillwell et al, 2004; Mack et al, 1998).
The mouse cDNA encoding ninein has been cloned by Bouckson-Castaing et al (1996). The gene has been cloned by Nagase et al (2000) as KIAA1565. Hong et al (2000) have cloned full-length
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