nigrocin-2ISb |
NIH 3T3 |
ZNF51 |
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Nigrocin-1 (GLLDSIKGMAISAGKGALQNLLKVASCKLDKTC) and Nigrocin-2 (GLLSKVLGVGKKVLCGVSGLC) are cationic antimicrobial peptides isolated from the skin of Rana nigromaculata (Pelophylax nigromaculatus, Black-spotted frog). Both peptides possess a broad spectrum of antimicrobial activity against various microorganisms with different specificity (Park et al, 2001). Nigrocin-1 has high sequence homology with brevinin-2. Nigrocin-2 has low sequence homology with any other known antimicrobial peptides. Wang L et al (2010) have identified cDNA clones for Nigrocin-2 homologs of four species
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