Neucrin |
neu differentiation factor |
terminally differentiated EM cells |
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This murine protein of 171 amino acids has been identified by Kimura et al (2005). Human neudesin shows approximately 91 % sequence similarity to mouse neudesin. The approved gene symbol is NENF [Neuron-derived neurotrophic factor]. In databanks the protein is identified also as SPUF protein [secreted protein of unknown function] (Rasheed et al, 1999) and human SCIRP10-related protein. Neudesin has been identified independently as CIR2 [Cell immortalization-related protein 2].
Neudesin is a secreted protein expressed abundantly in the developing brain and spinal cord in embryos (neurons
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