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Netrins

Netrin-1 (abbr. NTN1) and Netrin-2 (abbr. NTN2) were isolated as factors secreted from floor plate cells at the ventral midline of the embryonic spinal cord of chicken brain. The two Netrins are homologous to UNC6, a laminin-related protein required for the circumferential migration of cells and axons in Caenorhabditis elegans. Human netrin-1 and netrin-2 have been called NTN1L (netrin-1 like) and NTN2L (netrin-2 like), respectively. NTN1L (human ... ... ... ... ... Subscribe to continue reading! ... ...

 

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