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[natural killer T-cells] NKT-cells, called also NK-like T-cells [natural killer-like T-cells] or NK type T-cells, constitute a small fraction of circulating lymphocytes. Their development is thymus-dependent (Berzins et al, 2004; Pear et al, 2004; Pellicci et al, 2002; Gapin et al, 2001) and the development of at least some subsets requires IL7 (Sandberg et al, 2004) or IL15 (Ranson et al, 2003).

NKT-cells and NK-cells share expression of some cell surface antigens, including expression of NK1.1 (Godfrey et al, 2004). By definition, NKT-cells are specialized T-cells because they express the T-cell receptor. NKT-cells ... ... ... ... ... Subscribe to continue reading! ... ...


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