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NK-RIF

[natural killer resistance inducing factor] This biochemically uncharacterized factor of approximately 36 kDa is found in the conditioned medium of some tumor cells (Serrano et al, 1989). It blocks the cytotoxic activity of NK-cells. It does not block the binding capacity of the target and effector cells, nor does it affect target susceptibility to LAK cells or cytotoxic T-cells.

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Entry last modified: January 2008

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