NDSP

[neuroblastoma-derived secretory protein] This secreted protein has been described by Vasudevan et al (2009). The approved gene symbol for NDSP is FAM163A [family with sequence similarity 163 member A]. Another designation is C1orf76 [chromosome 1 open reading frame 76].

NDSP is a protein of 167 amino acids (18 kDa) overexpressed specifically in neuroblastoma cells and cell lines at much higher levels than other adult and pediatric malignancies and normal tissues. The inhibition of NDSP expression in neuroblastoma cell lines decreases cellular proliferation and growth in a colony formation assay. NDSP serves as a growth factor for ... ... ... ...
 
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Entry last modified: December 2014