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NAP4

[Nck-associated protein-4] Don't confuse with NAP-4 [neutrophil-activating protein-4].

The gene encoding this protein has been identified by Matuoka et al (1997). The protein contains an SH2 domain and binds to Nck, ASH (GRB2), and phospholipase C-gamma. The SH2 domain of NAP4 also binds activated and tyrosine-phosphorylated EGF receptor.

Sequence analysis shows that the encoded protein is the same as SOCS7.

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