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Matrixins

This term has been proposed as a collective term for members of the family of matrix metalloproteinases (Nagase et al, 1992). For an early overview summarizing the chief characteristics of these enzymes (zinc dependence, secretion in zymogen form, activation of zymogens by proteinases, sequence homology to collagenase, extracellular matrix components as subsrate, inhibition by tissue inhibitors of metalloproteinases) see also: Woessner et al (1991).

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