MT5-MMP

[Membrane-type matrix metalloproteinase-5] Also: MT-MMP-5. The gene is known as MMP-24.

This membrane-bound matrix metalloproteinase has been isolated from a mouse brain cDNA library (Llano et al, 1999). It is organized like the other Membrane-type matrix metalloproteinases and is expressed in a brain-specific manner (Llano et al, 1999; Jaworski, 2000; Bernal et al, 2005). Llano et al (1999) and Pei (1999) have shown that MMP-24 contains a hemopexin domain.

Sekine-Aizawa et al (2001) have localized MT5-MMP to neurons and shown that in the cerebellum, its expression is regulated developmentally and is closely associated with dendritic tree formation of ... ... ... ...
 
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Entry last modified: March 2006